分子生物学研究室

1. Wang N, Li Y, Zhou RM, Cui SJ, Cao SR, Huang X, Huo XR, Shan BE.  The effect of polymorphisms in the promoter of the BIRC5 gene on the risk of oesophagealsquamous cell carcinoma and patient's outcomes. Mutagenesis. 2019 Jun 3. pii: gez012. doi: 10.1093/mutage/gez012.

2. Yang Y, Wu L, Shu X, Lu Y, Shu XO, Cai Q, Beeghly-Fadiel A, Li B, Ye F, Berchuck A, Anton-Culver H, Banerjee S, Benitez J, Bjørge L, Brenton JD, Butzow R, Campbell IG, Chang-Claude J, Chen K, Cook LS, Cramer DW, DeFazio A, Dennis J, Doherty JA, Dork T, Eccles DM, Velez Edwards D, Fasching PA, Fortner RT, Gayther SA, Giles GG, Glasspool RM, Goode EL, Goodman MT, Gronwald J, Harris HR, Heitz F, Hildebrandt MAT, Høgdall E, Høgdall CK, Huntsman DG, Kar SP, Karlan BY, Kelemen LE, Kiemeney LA, Kjaer SK, Koushik A, Lambrechts D, Le ND, Levine DA, Massuger LFAG, Matsuo K, May T, McNeish IA, Menon U, Modugno F, Monteiro AN, Moorman PG, Moysich KB, Ness RB, Nevanlinna H, Olsson H, Onland-Moret NC, Park SK, Paul J, Pearce CL, Pejovic T, Phelan CM, Pike MC, Ramus SJ, Riboli E, Rodríguez-Antona C, Romieu I, Sandler DP, Schildkraut JM, Setiawan VW, Shan K, Siddiqui N, Sieh W, Stampfer MJ, Sutphen R, Swerdlow AJ, Szafron LM, Teo SH, Tworoger SS, Tyrer JP, Webb PM, Wentzensen N, White E, Willett WC, Wolk A, Woo YL, Wu AH, Yan L, Yannoukakos D, Chenevix-Trench G, Sellers TA, Pharoah PDP, Zheng W, Long J. Genetic data from nearly 63,000 women of European descent predicts DNA methylation biomarkers and epithelial ovarian cancer risk. Cancer Res. Cancer Res. 2019 Feb 1;79(3):505-517.

3. Wang L, Zhao J, Li Y, Wang Z, Kang S. Genome-wide analysis of DNA methylation in endometriosis using Illumina Human Methylation 450 K BeadChips. Mol Reprod Dev. 2019 May;86(5):491-501.

4. Lawrenson K, Song F, Hazelett DJ, Kar SP, Tyrer J, Phelan CM, Corona RI, Rodríguez-Malavé NI, Seo JH, Adler E, Coetzee SG, Segato F, Fonseca MAS, Amos CI, Carney ME, Chenevix-Trench G, Choi J, Doherty JA, Jia W, Jin GJ, Kim BG, Le ND, Lee J, Li L, Lim BK, Adenan NA, Mizuno M, Park B, Pearce CL, Shan K, Shi Y, Shu XO, Sieh W; Australian Ovarian Cancer Study Group, Thompson PJ, Wilkens LR, Wei Q, Woo YL, Yan L, Karlan BY, Freedman ML, Noushmehr H, Goode EL, Berchuck A, Sellers TA, Teo SH, Zheng W, Matsuo K, Park S, Chen K, Pharoah PDP, Gayther SA, Goodman MT. Genome-wide association studies identify susceptibility loci for epithelial ovarian cancer in east Asian women. Gynecol Oncol. 2019 May;153(2):343-355.

5. Zhao J, Wang L, Li Y, Zhao W, Kang S. Hypomethylation of the GSTM1 promoter is associated with ovarian endometriosis. Hum Reprod. 2019 May 1;34(5):804-812.

6. Zhao W, Kang S, Zhao J, Wang L, Cao S, Li Y. Aberrant methylation of the IL-12B promotor region contributes to the risk of developing ovarian endometriosis. Mol Reprod Dev. 2019 Jun;86(6):632-638.

7. Si W, Kang S, Sun H, Chen J, Cao S, Li Y. Genetic polymorphisms in hMSH2 and hMLH1 genes are associated with prognosis in epithelial ovarian cancer patients. Int J Gynecol Cancer. 2019 Sep;29(7):1148-1155.

8. Huang X, Hao YL, Zhen XL, et al. Association between the vascular endothelial growth factor gene polymorphisms and the risk of polycystic ovary syndrome in Northern Chinese women. Gynecol Endocrinol, 2019, 4(2):1-4.

9. Zhou RM, Li Y, Liu JH, Wang N, Huang X, Cao SR, Shan BE. Programmed death-1 ligand-1 gene rs2890658 polymorphism associated with the risk of esophageal squamous cell carcinoma in smokers.      Cancer Biomarkers, 2018, 21 (1): 65-71.

10. Zhou RM, Li Y, Wang N, Huang X, Cao SR. Phospholipase C ε-1 gene polymorphisms and prognosis of esophageal cancer patients from a high-incidence region in northern China. Mol Clin Oncol. 2018, 8 (1): 170-174.

11. Li Y, Hao N, Wang YX, Kang S. Association of Endometriosis-Associated Genetic Polymorphisms From Genome-Wide Association Studies With Ovarian Endometriosis in a Chinese Population Reprod Sci. 2017 Jan;24(1):109-113

12. Li Y, An D, Guan YX, Kang S. Aberrant Methylation of the E-Cadherin Gene Promoter Region in Endometrium and Ovarian Endometriotic Cysts of Patients with Ovarian Endometriosis. Gynecol Obstet Invest. 2017;82(1):78-85.

13. Li Y, Zhang HL, Kang S, Zhou RM, Wang N. The effect of polymorphisms in PD-1 gene on the risk of epithelial ovarian cancer and patients' outcomes. Gynecol Oncol. 2017 Jan; 144(1): 140-145.

14. Li Y, Zhang HL, Kang S, Zhou RM, Wang N. The effect of polymorphisms in PD-1 gene on the risk of epithelial ovarian cancer and patients' outcomes. Gynecol Oncol. 2017 Jan;144(1):140-145.

15. Juan W, Shan K, Na W, Rong-Miao Z, Yan L. The Associations of Genetic Variants in E-cadherin Gene With Clinical Outcome of EpithelialOvarian Cancer. Int J Gynecol Cancer. 2016 Nov;26(9):1601-1607.

16. Li Y, Ran R, Guan Y, Zhu X, Kang S. Aberrant Methylation of the E-Cadherin Gene Promoter Region in the Endometrium of Women With Uterine Fibroids. Reprod Sci. 2016 Aug;23(8):1096-102.

17. Zhou RM, Li Y, Wang N, Huang X, Cao SR, Shan BE*, Association of programmed death-1 polymorphisms with the risk and prognosis of esophageal squamous cell carcinoma, Cancer Genet, 2016, 209(9):365-375

18. Zhou RM, Niu CX, Wang N, Liu L, Huang X, Chen ZF, Huo XR, Hao YL, Li Y*, XPG Gene Polymorphisms and the Risk of Gastric Cardia Adenocarcinoma, Genet Test Mol Biomarkers, 2016, 20(8): 432-437