病理学研究室

近3年SCI发表情况：

1） Guo W, Dong Z, Guo Y, Shen S, Guo X, Kuang G, Yang Z. Decreased expression and frequent promoter hypermethylation of RASSF2 and RASSF6 correlate with malignant progression and poor prognosis of gastric cardia adenocarcinoma. Mol Carcinog. 2016; 55(11): 1655-1666.  

2） Guo W, Dong Z, Cui J, Guo Y, Shen S, Guo X, Kuang G. Aberrant hypermethylation of RASSF2 in tumors and peripheral blood DNA as a biomarker for malignant progression and poor prognosis of esophageal squamous cell carcinoma. Clin Exp Metastasis. 2016; 33(1): 73-85.

3） Liu Y, Dong Z, Liang J, Guo Y, Guo X, Shen S, Kuang G, Guo W. Methylation-mediated repression of potential tumor suppressor miR-203a and miR-203b contributes to esophageal squamous cell carcinoma development. Tumour Biol. 2016; 37(4):5621-5632.

4） Guo W, Dong Z, Shi Y, Liu S, Liang J, Guo Y, Guo X, Shen S, Wang G. Methylation-mediated downregulation of long noncoding RNA LOC100130476 in gastric cardia adenocarcinoma. Clin Exp Metastasis. 2016; 33(5):497-508.

5） Guo W, Dong Z, Shi Y, Liu S, Liang J, Guo Y, Guo X, Shen S, Shan B. Aberrant methylation-mediated downregulation of long noncoding RNA LOC100130476 correlates with malignant progression of esophageal squamous cell carcinoma. Dig Liver Dis. 2016; 48(8):961-969.

6） Liu W, Dong Z, Liang J, Guo X, Guo Y, Shen S, Kuang G, Guo W. Downregulation of potential tumor suppressor miR-203a by promoter methylation contributes to the invasiveness of gastric cardia adenocarcinoma. Cancer Invest. 2016; 34(10):506-516.

7） Guo YL, Zhu TN, Guo W, Dong ZM, Zhou Z, Cui YJ, Zhao RJ. Aberrant CpG Island Shore Region Methylation of CAV1 Is Associated with Tumor Progression and Poor Prognosis in Gastric Cardia Adenocarcinoma. Arch Med Res. 2016, 47(6):460-470.

8） Han L, Liu S, Liang J, Guo Y, Shen S, Guo X, Dong Z, Guo W. A genetic polymorphism at miR-526b binding-site in the lincRNA-NR_024015 exon confers risk of esophageal squamous cell carcinoma in a population of north China. Mol Carcinog. 2017; 56(3):960-971.

9） Guo X, Dong Z, Yamada S, Li Y, Guo Y, Shen S, Liang J, Tanimoto A, Guo W. Association of Casp3 microRNA Target Site (1049216) SNP With the Risk and Progress of Cervical Squamous Cell Carcinoma. Int J Gynecol Cancer. 2017; 27(2):206-213.

10） Guo YL, Shan BE, Guo W, Dong ZM, Zhou Z, Shen SP, Guo X, Liang J, Kuang G. Aberrant methylation of DACT1 and DACT2 are associated with tumor progression and poor prognosis in esophageal squamous cell carcinoma. J Biomed Sci. 2017; 24(1):6.

11） Guo W, Dong Z, Liu S, Qiao Y, Kuang G, Guo Y, Shen S, Liang J. Promoter hypermethylation-mediated downregulation of miR-770 and its host gene MEG3, a long non-coding RNA, in the development of gastric cardia adenocarcinoma. Mol Carcinog. 2017; 56(8):1924-1934.

12） Dong Z, Zhang A, Liu S, Lu F, Guo Y, Zhang G, Xu F, Shi Y, Shen S, Liang J, Guo W. Aberrant Methylation-mediated Silencing of lncRNA MEG3 Functions as a ceRNA in Esophageal Cancer. Mol Cancer Res. 2017; 15(7):800-810.

13） Guo W, Liu S, Dong Z, Guo Y, Ding C, Shen S, Liang J, Shan B. Aberrant methylation-mediated silencing of lncRNA CTC-276P9.1 is associated with malignant progression of esophageal squamous cell carcinoma. Clin Exp Metastasis. 2018; 35(1-2):53-68.

14） Guo W, Lv P, Liu S, Xu F, Guo Y, Shen S, Liang J, Kuang G, Dong Z. Aberrant methylation-mediated downregulation of long noncoding RNA C5orf66-AS1 promotes the development of gastric cardia adenocarcinoma. Mol Carcinog. 2018; 57(7):854-865.

15） Li S, Li T, Li X, Yao Y, Jiang X, Zhao L, Guo W. MicroRNA-32 regulates development and progression of hepatocellular carcinoma by targeting ADAMTS9 and affects its prognosis. Med Sci Monit Basic Res. 2018; 24:177-187.

16） Guo W, Liang X, Liu L, Guo Y, Shen S, Liang J, Dong Z. MiR-6872 host gene SEMA3B and its antisense lncRNA SEMA3B-AS1 function synergistically to suppress gastric cardia adenocarcinoma progression. Gastric Cancer. 2019; 22(4): 705-722.

17） Dong Z, Liang X, Wu X, Kang X, Guo Y, Shen S, Liang J, Guo W. Promoter hypermethylation-mediated downregulation of tumor suppressor gene SEMA3B and lncRNA SEMA3B-AS1 correlates with progression and prognosis of esophageal squamous cell carcinoma. Clin Exp Metastasis. 2019; 36(3): 225-241.